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Jin LV 吕金

Post-doctoral Fellow

Email:

A Bit About Me

Human gut harbors trillions of microorganisms, which play pivotal role in modulating human development, physiology and pathology. I’m fascinated with the communication between the two kingdoms, and believe that the microbial metabolites serves as one of the major messengers. With my past work experience in microbial metabolism, combined with Wu lab’s expertise in immunology and genetics, I hope to discover novel molecular mechanisms by which microbial metabolites affect immune function in health and disease.

EDUCATION

  • Ph.D. in Biology, China studies, Shanghai Jiao Tong University at Shanghai, Jan 2013-Jan 2021

  • M.S. in Microbiology, Central China Normal University, Wuhan, Jan 2010- Jun2013

  • B.S. in Biological and pharmaceutical engineering, Wuhan Polytechnic University, Wuhan, Jan 2007-Jun 2009

PUBLICATIONS:

  • Lü J, Long Q, Zhao Z, Chen L, He W, Hong J, Liu K, Wang Y, Pang X, Deng Z, Tao M*. Engineering the Erythromycin-Producing Strain Saccharopolyspora erythraea HOE107 for the Heterologous Production of Polyketide Antibiotics. Front Microbiol. 2020;11:3061. doi:10.3389/fmicb.2020.593217

  • Peng Q, Gao G, Lü J, Long Q, Chen X, Zhang F, Xu M, Liu K, Wang Y, Deng Z, Li Z, Tao M*. Engineered Streptomyces lividans strains for optimal identification and expression of cryptic biosynthetic gene clusters. Front Microbiol. 2018;9. doi:10.3389/fmicb.2018.03042

  • Gao G, Liu X, Xu M, Wang Y, Zhang F, Xu L, Lü J, Long Q, Kang Q, Ou HY, Wang Y, Rohr J, Deng Z, Jiang M*, Lin S*, Tao M*. Formation of an angular aromatic polyketide from a linear anthrene precursor via oxidative rearrangement. Cell Chem Biol. 2017;24(7):881-891.e4. doi:10.1016/j.chembiol.2017.06.008

  • Chen X, Xu M, Lü J, Xu J, Wang Y, Lin S, Deng Z, Tao M*. Biosynthesis of tropolones in Streptomyces spp.: interweaving biosynthesis and degradation of phenylacetic acid and hydroxylations on the tropone ring. Vieille C, ed. Appl Environ Microbiol. 2018;84(12):e00349-18. doi:10.1128/AEM.00349-18

  • Lü J, He Q, Huang L, Cai X, Guo W, He J, Zhang L, Li A*. Accumulation of a bioactive benzoisochromanequinone compound kalafungin by a wild type antitumor-medermycin-producing streptomycete strain. PLoS One. 2015 Feb 19;10(2):e0117690. doi: 10.1371/journal.pone.0117690.

  • Lü J, Wu X, Jiang Y, Cai X, Huang L, Yang Y, Wang H, Zeng A, Li A*. An extremophile Microbacterium strain and its protease production under alkaline conditions. J Basic Microbiol. 2014 May;54(5):378-85. doi: 10.1002/jobm.201200553.

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